Promiscuous Protein Binding as a Function of Protein Stability
نویسندگان
چکیده
منابع مشابه
Phosphorylation in protein-protein binding: effect on stability and function.
Posttranslational modifications offer a dynamic way to regulate protein activity, subcellular localization, and stability. Here we estimate the effect of phosphorylation on protein binding and function for different types of complexes from human proteome. We find that phosphorylation sites tend to be located on binding interfaces in heterooligomeric and weak transient homooligomeric complexes. ...
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ژورنال
عنوان ژورنال: Structure
سال: 2017
ISSN: 0969-2126
DOI: 10.1016/j.str.2017.11.002